Opioids Addiction Watch

Empire of Pain: Story Behind Prescription Opioids Overdose Epidemic

The New Yorker has a very detailed investigative article The Family That Built an Empire of Pain. From the article, it appears that The Sackler family which owns Purdue Pharma, the maker of OxyContin (active ingredient oxycodone, a chemical cousin of heroine). Since 1999, over two hundred thousands Americans have died because of OxyContin & prescription opioids overdose. A must read article to understand the entire prescription overdose epidemics.

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There is a brief note in The New York Times explaining Why Onions Make Us Cry? It turns out that when we cut onions it releases  a chemical called lachrymatory factor (LF) which irritates our eyes. LF is by product of two molecules located in cells: sulfenic acid precursor floating around and a protein called alliinase in cytoplasm, which are released when onions are crossed and produce irritating LF. This chemical is used by plants as defense mechanisms from microbes & animals. An undergraduate student Josie Silvaroli, an undergraduate at Case Western Reserve University in Ohio helped explained this puzzle in a paper published in ACS Chemical Biology in July 2017.

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